Abstract

Prostate cancer is a significant disease for men and it became a truly prevalent cancer even in Asian countries including Korea. Several important factors such as dietary factors, lifestyle-related factors and androgen have been recognized as contributors to the risk of prostate cancer. Recently, it has been suggested that chronic inflammation is related to the development of prostate cancer. A body of literature tells us about the possible links between sexually transmitted infection, chronic prostatitis and prostate cancer. Furthermore, some studies concerning several genes associated with the immunologic aspects of inflammation and somatic alterations of genes involved in defense against inflammatory damage and in tissue recovery are also reported to be related to the development of prostate cancer. Here, we review the evidences of link between chronic inflammation and prostate cancer.

• Keywords: Prostate, Cancer, Inflammation