Abstract

Lower urinary tract symptoms (LUTS) are related to urination, pain/discomport, or both. The prevalence of LUTS in the community is high in men and increases with age. LUTS are an important clinical manifestation of prostate. Benign prostatic hyperplasia (BPH) and prostatitis are the most common benign diseases of the prostate and induce LUTS. Recently, many researches have shown roles of chronic inflammation in BPH and chronic prostatitis/chronic plevic pain symdrome (CP/CPPS). Although the pathogenesis of BPH and CP/CPPS is still unresolved, chronic inflammation may play a significant role in disease progression of LUTS. This review presents recent evidence that suggests a relationship between inflammation and BPH and CP/CPPS.

• Keywords: Benign prostatic hyperplasia, Prostatitis, Inflammation