"Purpose: We conducted a retrospective analysis of acute bacterial prostatitis (ABP) to evaluate the factors of progressing to chronic bacterial prostatitis (CBP) and inflammatory chronic pelvic pain syndrome (CPPS) from ABP. Materials and Methods: The clinical records of 480 cases compatible with a confirmed diagnosis of ABP from five urological centers between 2001 and 2010 were reviewed. We defined chronic infection (CI) as a progression to CBP and inflammatory CPPS after treatment of ABP in admission periods when followed-up at 3 months or more. Results were analyzed according to two groups: recovered without CI (group A, n=428) and developed to CI (group B, n=52). Results: Of the 480 ABP patients, 1.3% (6/480) progressed to CBP and 9.6% (46/480) progressed to inflammatory CPPS. The progression rate of CI was 10.9% (52/480). The factors that affected progress to CI were diabetes, prior manipulation, prostate volume, absence of cystostomy and urethral catheterization (p<0.05). Conclusions: The identification and characterization of influential factors may accelerate the development of preventive, diagnostic and therapeutic strategies for the treatment of CI from ABP."