Urogenital Tract Infection

Artificial Intelligence for Autonomous Robotic Surgery in Urology: A Narrative Review: Dae Young Lee, Hee Jo Yang; Urogenit Tract Infect 2024;19(3):80-88. Published online December 31, 2024; DOI: https://doi.org/10.14777/uti.2448020010

Abstract PDF PubReader ePub: Artificial intelligence (AI) has emerged as a transformative force in various sectors, including medicine, where it processes high-dimensional data to improve diagnostics and treatment outcomes. This review explores AI applications in urological surgery, highlighting advancements such as image classification and robotic assistance in surgical procedures. AI has demonstrated exceptional diagnostic accuracy, with some systems achieving up to 99.38% in detecting prostate cancer. Additionally, AI facilitates real-time anatomical recognition and instrument delineation, increasing surgical precision. While current robotic systems operate under human supervision, ongoing research aims to advance autonomous surgical capabilities. The future of AI in robotic surgery is promising, especially regarding the possibility of improved outcomes; nonetheless, challenges related to autonomy, safety, and ethics remain.

The Urinary Microbiome: A Pediatric Urological Perspective: Sang Don Lee, Jae Min Chung; Urogenit Tract Infect 2022;17(3):61-70. Published online December 31, 2022; DOI: https://doi.org/10.14777/uti.2022.17.3.61

Abstract PDF PubReader ePub: The human microbiome is currently being studied with increasing interest. The microbiome refers to the microorganisms living in the body and their genetic information. The human body is known to contain 1.3 to 10 times more microorganisms than human cells. The Human Microbiome Project was started in 2007 to characterize the human microbiome and analyze its role in human health and diseases. Based on the recent microbiome literature, alterations in the microbiome are associated with several non-urological diseases in pediatrics, such as infantile colic, necrotizing enterocolitis, asthma, atopy, obesity, type-1 diabetes, autism, atopic dermatitis, psoriasis, and bronchial asthma. While some urinary microbiome studies (including prostate cancer, bladder cancer, interstitial cystitis, urge urinary incontinence, overactive bladder, stone disease, and urinary tract infections) have been conducted in adults, there are very few pediatric urinary microbiome studies. This study reviews the role of the urinary microbiome in urinary tract diseases from a pediatric urological perspective.

The Effects of Short-Chain Fatty Acids in Urological Diseases: Hee Jo Yang, Doo Sang Kim; Urogenit Tract Infect 2022;17(1):8-13. Published online April 30, 2022; DOI: https://doi.org/10.14777/uti.2022.17.1.8

Abstract PDF PubReader ePub: The gut microbiome, believed to serve as a second genome within the human body, is involved in the regulation of several metabolic processes. These include human gene expression, development, nutrition and homeostasis. Dysbiosis, is an imbalance in the gut microbiome, which is known to be associated with various disease conditions such as Crohn's disease and Clostridium infections. The gut microbiota communicates with the host through a variety of biomolecules, nutrient signal-independent pathways, and epigenetic mechanisms. The gut microbiota supports the digestion and absorption of food, metabolizes fiber into bioactive short-chain fatty acids (SCFA), produces vitamins and nutrients, maintains gut integrity, and modulates host immunity. Among the above, there has been great interest in SCFA in microbiome research due to its beneficial effects on the intestinal barrier function and systemic anti-inflammatory effects. Recent reports have also indicated the role of SCFA in obesity, insulin resistance, and type 2 diabetes. While SCFA are associated with reduced risk of various diseases, dysbiosis and altered SCFA fermentative pathways could result in disease. This article is a review on the role of SCFA in urological diseases.

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