Urogenital Tract Infection

Volume 16 (1); April 2021

Review

Systematic Literature Review of the Urological Field and Considerations in COVID-19: Joongwon Choi, Hyun Soo Ryoo, Jae Hyun Ryu, Yun Beom Kim, Seung Ok Yang, Jeong Kee Lee, Tae Young Jung, Jung Hoon Kim, Tae-Hyoung Kim; Urogenit Tract Infect 2021;16(1):1-7. Published online April 30, 2021; DOI: https://doi.org/10.14777/uti.2021.16.1.1

Abstract PDF PubReader ePub: Coronavirus disease 2019 (COVID-19) was declared a worldwide pandemic in March 2020 after originating in China. Widespread uncertainty resulting from the pandemic has revolutionized urology practice worldwide, similar to that observed in other fields. The urological manifestations of COVID-19 were investigated by performing a literature search using a combination of keywords related to COVID-19 and urology. To date, COVID-19 has not been associated with any lower urinary tract symptoms, and there is no level 1 evidence that associates it with urinary malignancy and urolithiasis. Viral RNA has been detected in urine (5.74%), but there is no evidence of actual infection via urine. COVID-19 has transformed the standard urological practice into crisis-based care and has changed the medical and surgical priorities dramatically in the field. Most hospitals have established quarantine guidelines for each hospital, and procedures must be performed according to the present circumstances. Furthermore, in the absence of high-level evidence, specific efforts are needed to minimize the risk of COVID-19 infections during care.

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Original Articles

Efficacy and Tolerability of Solifenacin Fumarate with Overactive Bladder Patients: A Multicenter Observational Study: Jae Hun Shim, Se Young Choi, Joon Hee Gook, Yong-June Kim, Woo Heon Cha, Dae Hee Kim, Kyeong Hee Kim, Young Woong Park, Jin Mo Um, Il Sung Lim, Kyung Keun Seo, Kyu Seon Cho, Young Jae Lee, Mi-Kyung Lee, Tae-Hyoung Kim; Urogenit Tract Infect 2021;16(1):8-15. Published online April 30, 2021; DOI: https://doi.org/10.14777/uti.2021.16.1.8

Abstract PDF PubReader ePub: Purpose: Overactive bladder (OAB) is characterized by a series of highly prevalent symptoms among older adults. This study used the Overactive Bladder Symptom Score (OABSS) and Patient Perception of Bladder Condition (PPBC) tools to evaluate the efficacy and stability of solifenacin fumarate in the treatment of OAB.
Materials and Methods: This was a prospective, multicenter, single-arm, 12-week study that enrolled 163 OAB patients. The patients received 5 mg/day of solifenacin fumarate. The changes in the OABSS, symptoms, and PPBC scores were evaluated at 0, 4, and 12 weeks. Subgroup analysis of the OABSS and PPBC scores based on sex, diabetes mellitus (DM) status, and body mass index (BMI) were also evaluated.
Results: At the baseline (week 0), the mean OABSS for all patients was 8.45±2.38 (p=0.199). Subsequently, the mean OABSS declined to 5.41±2.69 (p=0.255) at four weeks and 4.21±2.61 (p=0.240) at 12 weeks. The OABSS subscore and PPBC score decreased significantly during the study (p<0.01). After cases were stratified according to sex, DM status, and BMI, the mean OABSS (mean and subscore) and PPBC score at four and 12 weeks were also improved significantly relative to the baseline scores (both p<0.05). The overall incidence of adverse events was 7.36% (12 cases), and three patients (1.82%) permanently discontinued solifenacin fumarate because of the adverse events.
Conclusions: Solifenacin fumarate is a safe and effective treatment alternative for relieving OAB symptoms, considering the balance between the efficacy, patientsʼ well-being, and tolerability.

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Syphilis Notification Systems in Korea over the Last 20 Years: Yumi Seo, Gilho Lee; Urogenit Tract Infect 2021;16(1):16-23. Published online April 30, 2021; DOI: https://doi.org/10.14777/uti.2021.16.1.16

Abstract PDF Supplementary Material PubReader ePub: Purpose: The syphilis notification system has been revised three times in Korea during the last 20 years. Accordingly, we evaluated the performance of the three systems by analyzing data from the Korea Disease Control and Prevention Agency (KDCA).
Materials and Methods: We analyzed trends of stage 1, 2, and congenital syphilis cases reported in the KDCA from 2001 to 2010 in the 1st sentinel (S1), from 2011 to 2019 in the 1st universal (U1), and 2020 in the 2nd sentinel (S2) notification system.
Results: A total of 21,820 syphilis cases were reported, 9,177 cases in S1, 12,321 in U1, and 322 in S2, respectively. The reported cases can be presented in the form of four expanding waves across the time period. Although the most commonly reported age group with infection was 20-29 years in all three reporting systems, the pattern of infections was different; the number of older patients was relatively high in the S1 group while the number of syphilis cases declined sharply in the older than 20-29 old age group in the U1 and S2 systems. Also, there was a sex-based difference in the three groups; the data from S1 were female-dominant but the data in U1 and S2 were male-dominant.
Conclusions: Our results showed that the universal notification system (U1) is superior in both the quantity and quality of data to the previous sentinel system (S1). The results from the new system, S2, are similar to those from U1.

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