-
Risk Factors of Sepsis in Obstructive Acute Pyelonephritis Associated with Urinary Tract Calculi
-
Chae Hong Lim, Jae Seung Hwang, Dae Ji Kim, Seok Heun Jang, Jeong Hwan Son, Dae Sung Cho, Jae Won Lee
-
Urogenit Tract Infect 2015;10(2):108-111. Published online October 31, 2015
-
-
-
 Abstract
 PDF
- Purpose: The aim of this study is to identify the risk factors for development of sepsis in patients with obstructive acute pyelonephritis (APN) associated with urinary tract calculi.
Materials and Methods: Between January 2004 and December 2013, 73 patients with obstructive APN associated with upper urinary tract calculi were admitted to our institution. Medical records of 73 patients (14 men and 59 women, mean age of 57 years) were reviewed retrospectively. The risk factors for sepsis were analyzed using multivariate logistic regression analysis.
Results: Of 73 patients, 37 (50.7%) developed sepsis. Old age and history of hypertension were more common in the sepsis group than in the non-sepsis group (p＜0.001 and p=0.018). The white blood cell count, neutrophil count, plateletto- lymphocyte ratio, neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein level were significantly higher in the sepsis group (p=0.011, p=0.001, p=0.042, p＜0.001 and p=0.006, respectively). Lymphocyte count, platelet count, and albumin level were significantly lower in the sepsis group (p＜0.001, p=0.008 and p＜0.001, respectively). Multivariate logistic regression analysis indicated that old age (odds ratio [OR], 2.13; p=0.023), decrease in serum albumin level (OR, 4.27; p=0.041), and high NLR (OR, 3.83; p=0.037) were independent risk factors for development of sepsis.
Conclusions: Elderly patients with obstructive APN associated with urinary tract calculi who have low serum albumin levels and high NLR should be treated carefully against development of sepsis.
-
Changes of Causative Organisms and Antibiotic Sensitivity of Urinary Tract Infection in the Southern Area of Kyoung-gi Do for Recent 4 Years
-
Jae Young Jeong, Jeong Hwan Son, Jae Il Kim, Seok Heun Jang
-
Korean J Urogenit Tract Infect Inflamm 2010;5(2):167-175. Published online October 31, 2010
-
-
-
Abstract
PDF
- "Purpose: We studied the changes in antibiotic sensitivity to causative organisms of urinary tract infection for the past 4 years, in order to provide useful information on the choice of adequate drugs for the treatment of urinary tract infection (UTI). Materials and Methods: We analyzed 7,938 uropathogens and their antibiotic sensitivities in 5,609 patients admitted or visited our hospital (located in the southern area of Kyoung-Gi Do) with more than 105cfu/ml of urine culture from January 2006 to December 2009 retrospectively. Results: The incidence of UTI increased with age and was highest in the first decade (33.0%), followed by seventh decade (11.9%). The most common pathogenic organism was E. coli (43.4%), followed by Klebsiella (13.6%), Enterococcus (7.9%), Staphylococcus (4.8%) and Serratia (4.6%). The incidence of E. coli and Klebsiella increased from respectively 39.3% and 10.1% in 2006, to 46.7% and 14.3% in 2009, while the incidence of Enterococcus and Staphylococcus decreased. In E. coli, resistance to antimicrobial agents was increased in ampicillin (69.6 to 72.0%), ciprofloxacin (38.4 to 47.0%), ceftazidime (12.3 to 19.0%), but decreased in trimethoprim/sulfamethoxazole (42.1 to 37%) and sensitivity to amikacine was above 90%. For the Gram-positive organisms, vancomycin and teicoplanin showed higher sensitivities. Conclusions: E. coli is the most common causative organism of UTI and its resistance to antimicrobial agents is increasing. Fluoroquinolone use should be restricted due to high resistance and economic. The use of amikacin or trimethoprim/sulfamethoxazole as empirical treatment for UTI should be considered. "
-
Combination Therapy of Corticostreroid and Tamoxifen for Retroperitoneal Fibrosis
-
Hyoung Chul Park, Eun Suk Kim, Eun Hong Jung, Seok Heun Jang, Joung Hwan Son
-
Korean J Urogenit Tract Infect Inflamm 2008;3(1):124-128. Published online April 30, 2008
-
-
-
Abstract
PDF
- Retroperitoneal fibrosis is a rare disease in which dominantly inflammatory mass envelops and potentially obstructs retroperitoneal structures including ureters. The initial management of retroperitoneal fibrosis depends on the patient's clinical status. About an emergent condition of a patient, we must have a initial management like resolution of ureteral obstruction. Recently, after initial management, the medical therapy in patient with retroperitoneal fibrosis is prefered to the surgical therapy. In this case, we report a female patient who underwent successful treatment of a retroperitoneal fibrosis with combined corticosteroid and tamoxifen.
|
KAUTI
