"Genitourinary tuberculosis is not very common but it is considered as a severe form of extra-pulmonary tuberculosis. Recently, the prevalence rate of genitourinary tuberculosis is increasing, even in developed countries where the incidence used to be low. The tuberculosis recrudescence was caused by the AIDS pandemic, emergence of resistant bacilli, human migration patterns, and world poverty. The diagnosis of genitourinary tuberculosis is made based on culture studies by isolation of the causative organism; however, biopsy material on conventional solid media may occasionally be required. Modern short-course anti-tuberculous drug regimens are effective in all forms of tuberculosis and is considered the first line therapy in genitourinary tuberculosis. And, radical or reconstructive surgery also necessary to treat of genitourinary tuberculosis. All urologist have to know genitourinary tuberculosis inside out and reduce a complication by early diagnosis and right medical and surgical treatment."