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- Review Treatment of Neisseria gonorrhoeae in the Era of Multidrug Resistance
- Ji Yun Chae, Mi Mi Oh
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다제내성 시대의 임균 치료 - 채지윤, 오미미
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Urogenital Tract Infection 2015;10(1):12-18.
Published online: April 30, 2015
Department of Urology, Korea University College of Medicine, Seoul, Korea
고려대학교 의과대학 비뇨기과학교실
고려대학교 의과대학 비뇨기과학교실
Received: 28 February 2014 • Revised: 18 March 2014 • Accepted: 25 March 2014
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Abstract
Neisseria gonorrhoeae (NG) is becoming increasingly less susceptible to the extended spectrum cephalosporin (ESC), which has been recommended for first-line treatment, and cases of treatment failure are being reported globally. An era of untreatable gonorrhea may have started, and it calls for novel treatment strategies. Essential actions should include use of higher doses of ceftriaxone administered as part of dual therapy and further development of alternative drug combinations. This review focuses on the global spread of ESC resistant NG and potential treatment options for the future.
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