Purpose: Urinary tract infection (UTI) is a relatively common disease, and clinically it appears diversely like urethritis, cystitis, prostatitis, and acute pyelonephritis. E. coli which is the major causative microorganism of UTI, and accounts for 50% of hospital pathogens cultured in 40% of catheter-related UTI. We evaluated the preventive effect on UTI and inhibitory effect on complications of Uro-vaxom?, and investigate the effect of Uro-vaxom? in catheter induced UTI.
Materials and Methods: A comprehensive electronic search was conducted using the Medline database to identify all publications relating to Uro-vaxom? and catheter and UTI by using keywords Uro-vaxom?, catheter, catheterization, urinary tract infection, cystitis, bacteriuria, antimicrobial agents, intensive care unit.
Results: 227 literatures which were consistent with our purposes were searched; we intensively analyzed 26 literatures which were appropriate for our literature. All literature reported antimicrobial effects of Uro-vaxom?.
Conclusions: We identified that Uro-vaxom? had a preventive effect on UTI associated with E. coli to patients who had catheterization. (Korean J UTII 2012;7:158-163)