Abstract

The human immunodeficiency virus (HIV) has been shown to be the causative agent of acquired immunodeficiency syndrome (AIDS). The first case of HIV infection in South Korea was detected in 1985. The HIV/AIDS epidemic is a complex one, with differing rates of infection in specific at-risk populations. In Korea, the male to female ratio was 9.4:1, and 72.9% of the patients were between 20 and 49 years of age. The major modes of transmission were sexual contacts, accounting for 83% of the cases (50.2% heterosexuals and 32.8% homosexuals) in 2008. Infection with HIV results in the progressive destruction of CD4+T lymphocytes, which cells are crucial to the normal function of the human immune system. After highly active antiretroviral therapy (HAART) decreased progression of AIDS, the mean period of disease progression is increased about 10years. Patients with HIV infection are prevented and controlled by medical, physical and psychological modalities. And other sexually transmitted disease was controlled simultaneously. In this review, it will be discussed up-to dated guideline of management of HIV infection and prevention of transmission and developing AIDS.

• Keywords: Human immunodeficiency virus, Guideline