Abstract

"The urogenital tract is the source of sepsis in 25% of all cases, mostly as a consequence of acute pyelonephritis, obstructive urolithiasis or renal abscess. Urosepsis is associated with a considerably high mortality rate of 20∼42%, especially in elderly patients, diabetics, and those under immunosuppression. Septic shock and multiorgan failure are the most common causes of death in affected individuals. Patients with urosepsis should be diagnosed at an early stage, especially in the case of a complicated urinary tract infection. Early tissue oxygenation, appropriate initial antibiotic therapy and rapid identification and control of the septic focus in the urinary tract are critical steps in the successful management of a patient with severe urosepsis. Urosepsis can due to both community- or nosocomial-acquired infections. Most nosocomial urosepsis can be avoided by measures used to prevent nosocomial infection such as reduction of hospital stay, early removal of indwelling urethral catheters, avoidance of unnecessary urethral catheterizations, correct use of closed catheter systems and attention to simple daily asepsis techniques in order to avoid crossinfection."

• Keywords: Urosepsis, Treatment, Prevention