A 66-year-old female patient presented with right upper quadrant pain for 3months. Preoperative computed tomography, magnetic resonance imaging, and laboratory tests were not consistent with findings of pheochromocytoma, but rather tumor originating from renal cortex. Pathology revealed pheochromocytoma and pancreatic injury was suspected after the surgery. Septic condition persisted despite of proper antibiotics, drainage, and octreotide therapy. Patient died on 8th day after radical nephrectomy. We report a morbid complication of pancreatic injury leading to septic shock and to death.