-
Antimicrobial Prophylaxis for Recurrent Urinary Tract Infection
-
Min Gu Park, Dae Yeon Cho
-
Korean J Urogenit Tract Infect Inflamm 2014;9(1):1-8. Published online April 30, 2014
-
-
-
 Abstract
 PDF
- Recurrent uncomplicated urinary tract infection (UTI) is a common problem in women, causing considerable morbidity and expense, and is a management burden for clinicians. In management of recurrent UTI, non-antimicrobial approaches to prevention of UTI, such as behavioral modifications should first be tried as a way of minimizing antimicrobial exposure, however, antimicrobial treatment of prophylaxis may be necessary in those who continue to have recurrences. Continuous antimicrobial prophylaxis, post-coital prophylaxis with low dose antimicrobials, and intermittent self-treatment with antimicrobials have all been shown to be effective in prevention of recurrent uncomplicated UTIs. The decision regarding which approach to use for prophylaxis depends on the frequency and pattern of recurrence and the patient’s preference to commit to a specific method. The risk of adverse events and the plan for pregnancy should be considered before starting any regimen of antimicrobial prophylaxis. The susceptibility of the organisms causing the previous UTIs and history of the patient’s drug allergies should be considered before selection of antimicrobials. Before initiation of any prophylaxis regimen, eradication of a previous UTI should be confirmed by a negative urine culture. Continuous antimicrobial prophylaxis is usually used for long periods, thus likely contributing to the widespread problem of antimicrobial resistance. Post-coital prophylaxis and self-treatment approach result in less antimicrobial use, but should be used in the appropriate settings.
-
Spinal Cord Injury and Urinary Tract Infection
-
Min Gu Park, Du Geon Moon
-
Korean J Urogenit Tract Infect Inflamm 2009;4(2):150-158. Published online October 31, 2009
-
-
-
Abstract
PDF
- Urinary tract infection (UTI) is the most frequently reported secondary impairment in individuals with spinal cord lesion (SCI). UTI is responsible for major morbidiry and mortality in SCI patients. Due to chronic bacterial infection within biofilms, an antibacterial treatment based on a urinary culture of bacteria in the urine and its antimicrobial susceptibility may fail to eradicate catheter associated UTI. The classic symptoms of UTI are unreliable indicators in SCI patients with neurogenic bladder. It is widely accepted that intermittent catheterization, when compared with indwelling catheters, reduces the risk of UTI in SCI patients and is the preferred method of bladder drainage in SCI patients. Guidelines for selecting antimicrobial agents in SCI patients are similar to guidelines for the treatment of complicated UTI in the general population.
|
KAUTI
