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The Influence of Past History of Prostatitis on the Risk Factor of Prostate Cancer
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Sung Yong Cho, Hyun Dong Song, In Rae Cho
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Korean J Urogenit Tract Infect Inflamm 2008;3(2):199-203. Published online October 31, 2008
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 Abstract
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- "Purpose: The study is carried out to investigate the influence of chronic prostatitis history on the risk factor of prostate cancer. Materials and methods: The investigation was proceeded with 64 patients diagnosed with prostate cancer through prostate biopsy from 2003 to 2006. We have surveyed the past history of prostatitis of the prostate cancer patients by a questionaires. The existence and nonexistence of past history of prostatitis divided the prostate cancer patients into two groups. We compared the differences between the groups of prostate cancer patients with the gleason score, clinical stage, prostate volume, protate specific antigen (PSA), prostate specific antigen density (PSAD), node invasion and metastatic lesion. Results: There were 15 patients (23.4%) among prostate cancer patients. In case of prostate cancer patients with past history of prostatitis, the mean age was 73.7±7.4, prostate volume 50.4±27.2ml, PSA 91.8±125.5 ng/ml, PSAD 1.8±2.8, respectively. The number of patients without past history of prostatitis were 49 and the mean age was 74.7±5.3years, prostate volume 43.2±20.4ml, PSA 33.9±46.1ng/ml and PSAD 0.7±0.8. There was significant difference in PSA and PSAD, but in the other factors were not. With Gleason score, clinical stage, node invasion and metastasis, there was no significant difference respectively. Conclusion: Our study demonstrates that the past history of prostatitis in prostate cancer patients increases the PSA. The past history of prostatitis may have influence on the PSA, and it can cause for confusion with the prognostic evaluation of prostate cancer."
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Effect of Chronic Pelvic Pain Syndrome on Sexual Function and Activity
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Keon Cheol Lee, Kyeong Hoon Lee, Hyun Dong Song, In Rae Cho
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Korean J Urogenit Tract Infect Inflamm 2008;3(1):75-80. Published online April 30, 2008
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Abstract
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- "Purpose: To evaluate whether patients with chronic pelvic pain syndrome (CPPS) have more sexual dysfunction rate than normal control, and whether the sexual dysfunction rate in CPPS increase with more severe CPPS symptom. Materials and Methods: 638 CPPS patients and 102 healthy controls were enrolled in this study. In all subjects, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), International Index of Erectile Function (IIEF) and the frequency of sexual intercourses per month during the last 3 months (F) were checked. Between CPPS patients and controls, scores of 5 domains of IIEF (erectile function: EF, intercourse satisfaction: IS, orgasmic function: OF, sexual desire: SD, overall satisfaction: OS) and F were compared. Erectile dysfunction (defined as < 26 EF domain score) rate was compared between the 2 groups. The CPPS patients were classified according to symptom severity into 3 groups and compared. Results: 289 CPPS patients and 67 controls were eligible for the analysis. F was 4.9, 6.5 for CPPS and control group, respectively (p=0.006). Total IIEF, IS, OF, SD and OS domain scores were lower in CPPS group (p<0.05) but EF domain scores were not different. Erectile dysfunction rate of CPPS and control group was 61.2% and 47.8%, respectively (p=0.043). CPPS patients were sub-classified as mild, moderate, severe symptom groups. The 3 groups were not different in age. In all domains of IIEF and F, no difference was found among the 3 groups. Conclusions: CPPS patients had higher sexual dysfunction rate and less sexual intercourses than healthy controls. But, CPPS symptom severity didn’t influence sexual frequency and dysfunction rate. It needs more extensive studies."
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KAUTI
