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Combination Therapy of Corticostreroid and Tamoxifen for Retroperitoneal Fibrosis
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Hyoung Chul Park, Eun Suk Kim, Eun Hong Jung, Seok Heun Jang, Joung Hwan Son
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Korean J Urogenit Tract Infect Inflamm 2008;3(1):124-128. Published online April 30, 2008
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Abstract
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- Retroperitoneal fibrosis is a rare disease in which dominantly inflammatory mass envelops and potentially obstructs retroperitoneal structures including ureters. The initial management of retroperitoneal fibrosis depends on the patient's clinical status. About an emergent condition of a patient, we must have a initial management like resolution of ureteral obstruction. Recently, after initial management, the medical therapy in patient with retroperitoneal fibrosis is prefered to the surgical therapy. In this case, we report a female patient who underwent successful treatment of a retroperitoneal fibrosis with combined corticosteroid and tamoxifen.
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Fournier's Gangrene on Penis, Scrotum, Perineum and Thigh
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Jae Young Jong, Taek Hwan Jang, Eun Seok Kim, Hyoung Chul Park, Tae Yeon Kim, Jae Il Kim
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Korean J Urogenit Tract Infect Inflamm 2007;2(2):212-216. Published online October 31, 2007
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Abstract
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- Genitourinary gangrene is an uncommon, potentially lethal disorder characterized by the abrupt onset of a rapidly progressive necrotizing soft tissue infection caused by the synergistic action of various organism that spread along fascial planes, causing subfascial soft tissue necrosis and destruction. Many factors, debilitating condition such as carcinoma, diabetes, and alcoholism etc, contribute to the development and perpetuate the course of Fournier's gangrene. In this case, predisposing causes were; perianal infection and chronic alcoholism. The cultured organism was Streptococcus pyogenes (group A beta-hemolytic Streptococcus). Massive wound debridement was done three times. Reconstructive surgery of defected penis, scrotum, buttock, thigh and perineum was performed after initial operation.
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